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InSilicoLab Features
InSilicoLab Feature
These features are exclusive to Portrai InSilicoLab.
Portrai InSilicoLab extends Portrai Explorer with advanced analysis capabilities designed for professional spatial transcriptomics research workflows.
What is InSilicoLab?
InSilicoLab is Portrai's cloud-based spatial transcriptomics analysis platform. It combines the visualization power of Portrai Explorer with server-side computational analysis tools, enabling:
- Differential expression analysis - Compare gene expression between cell populations
- Statistical testing - Rigorous statistical methods with multiple testing correction
- Scalable computation - Server-side processing for large datasets
Feature Comparison
| Feature | Core | InSilicoLab |
|---|---|---|
| Map Viewer and Facet View | Yes | Yes |
| Features, Import Metadata, Column Notes | Yes | Yes |
| Signatures | Yes | Yes |
| Subsetting | Yes | Yes |
| Plot Dashboard (Scatter, Violin, Bar, Stacked Bar, Dot, Box) | Yes | Yes |
| CSV and Image Export | Yes | Yes |
| DEG Analysis | - | Yes |
InSilicoLab-Exclusive Features
DEG Analysis
Differential Expression Gene (DEG) analysis allows you to identify genes that are significantly differently expressed between two or more cell populations.
Key capabilities:
- Define comparison groups using subsets
- Handle overlapping populations
- View results as heatmaps, volcano plots, and data tables
- Create signatures from selected result genes
- Filter by statistical significance (FDR)
- Filter by expression direction (up/down-regulated)
- Manage results (rename and delete saved analyses)
Accessing InSilicoLab Features
InSilicoLab features are available when using Portrai Explorer through the Portrai InSilicoLab platform. Look for additional icons in the Activity Bar:
| Icon | Feature | Description |
|---|---|---|
| DNA | DEG Analysis | Differential expression analysis |
Getting Started with InSilicoLab
- Access InSilicoLab - Log in to your Portrai InSilicoLab account
- Open a project - Select a spatial transcriptomics project
- Use Core features - All Core Portrai Explorer features are available
- Access InSilicoLab features - Click the additional icons in the Activity Bar
Related Topics
- DEG Analysis - Complete DEG analysis guide
- Subset - Subset conditions used in group definition
- Signatures - Create gene groups for analysis